Schedule
Every class meeting, with its lecture page and what to read in the course book.
Each row links to the lecture’s page, which lists its learning objectives, the slides and assignment, and the readings. Chapters of the course book appear in the last column as they are published.
Module 1 — Search and similarity
| Date | Meeting | Topic | Read in the book |
|---|---|---|---|
| Tue Aug 25 | Lecture 1.1 | Orientation | |
| Thu Aug 27 | Lecture 1.2 | The digital genome | |
| Tue Sep 1 | Lecture 1.3 | Sequence similarity | |
| Thu Sep 3 | Lecture 1.4 | Sequence alignment | |
| Tue Sep 8 | Lecture 1.5 | Heuristic search | |
| Thu Sep 10 | Lecture 1.6 | Read mapping | |
| Tue Sep 15 | Exam 1 |
Module 2 — Signal detection
| Date | Meeting | Topic | Read in the book |
|---|---|---|---|
| Thu Sep 17 | Lecture 2.1 | Signals in Sequences | |
| Tue Sep 22 | Lecture 2.2 | Signal or Noise? | |
| Thu Sep 24 | Lecture 2.3 | RNA quantification | |
| Tue Sep 29 | Lecture 2.4 | Differential Gene Expression | |
| Thu Oct 1 | Lecture 2.5 | Beyond the Bulk | |
| Tue Oct 6 | Exam 2 |
Module 3 — Physical modeling
| Date | Meeting | Topic | Read in the book |
|---|---|---|---|
| Thu Oct 8 | Lecture 3.1 | Protein structure | |
| Tue Oct 13 | Lecture 3.2 | Energy landscapes | |
| Thu Oct 15 | Lecture 3.3 | Molecular dynamics | |
| Tue Oct 20 | Lecture 3.4 | Structural analysis | |
| Thu Oct 22 | Lecture 3.5 | Structure prediction | |
| Tue Oct 27 | Exam 3 |
Module 4 — Cheminformatics
| Date | Meeting | Topic | Read in the book |
|---|---|---|---|
| Thu Oct 29 | Lecture 4.1 | Target identification | |
| Tue Nov 3 | Lecture 4.2 | The language of chemistry | |
| Thu Nov 5 | Lecture 4.3 | Molecular descriptors | |
| Tue Nov 10 | Lecture 4.4 | Molecular similarity | |
| Thu Nov 12 | Lecture 4.5 | Molecular property prediction | |
| Tue Nov 17 | Lecture 4.6 | Protein-ligand docking | |
| Thu Nov 19 | Exam 4 | ||
| Nov 23–29 | — | Thanksgiving recess (no classes) | |
| Tue Dec 1 | TBD | ||
| Thu Dec 3 | TBD | ||
| Dec 7–11 | Cumulative Final |